Endocrine Abstracts

Introduction: Primary hyperparathyroidism (pHPT) during pregnancy is rare and associated with increased morbidity for both mother and fetus. Maternal complications of pHPT include nepfhrolithiasis, pancreatitis, cardiac arrhytmias, hypertension, nausea and vomiting. pHPT is caused by a solitary adenoma in 85–90% of patients, and the curative treatment is parathyroidectomy. Here, we presented two women who have diagnosed pHPT and operated without complications in pregnancy...

Aim: To compare macular pigment optical density (MPOD) in diabetic and non-diabetic patients by using heterochromatic flicker photometry and to investigate the correlation of MPOD with glycosylated hemoglobin (HbA1C), serum lipid levels and vitamin D levels.Methods: Sixty-seven patients with 10/0 visual acuity were divided into group 1 (controls, n: 35) and group 2 (diabetics without retinopathy, n: 32). MPOD was measured with a heteroc...

Sarcoidosis is a multisystem granulomatous disease of unknown cause. The prevalence of neurosarcoidosis is about 5–15%. Hypothalamo-pituitary sarcoidosis is even rarer (<1% of cases evaluated for sellar and stalk lesions).Case Report: A 33-year-old man presented to urology department with erectile dysfunction which started six months ago. Hormonal evaluation revealed gonadotropin deficiency and hyperprolactinemia (Total testosterone: 30.5 ng/dl,...

Introduction: Association between high thyrotrophin receptor antibodies (TRAb) and relapse of thyroid cancer in Graves’ patients was reported previously. In this study, we aimed to investigate possible relation between TRAb and thyroid malignancies in patients with toxic multinodular (TMNG) and toxic nodular goiter (TNG).Methods: Thyroidectomized patients with a preoperative diagnosis of TMNG, TNG and euthyroid multinodular or nodular goiter (MNG/NG...

Introduction: The predictors of malignancy are important for decision of appropriate management in nodules with atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS). Our aim was to determine the ultrasonographical, clinical and biochemical predictors of malignancy in these patients.Methods: A total of 427 patients with Bethesda Category III (AUS/FLUS) thyroid nodules were included in this retrospective study. We d...

Introduction: Thyrolipoma (focal adenolipoma of thyroid gland) and thyrolipomatosis (diffuse lipomatosis in the gland) are rarely encountered pathologies in daily practice. We reported a case of small thyrolipoma incidentally diagnosed in a multinodular goiter patient.Case report: A 56 year-old man was admitted to our out-patient clinics with the complaint of a lump in his cervical region. His thyroid function tests were normal. In physical examination, ...

Introduction: In recent years, due to the improvements in ultrasonography (US), it has become possible to gain more information about the papillary throid carcinoma (PTC) and papillary tyroid microcarcinoma (PTMC). However, whether PTC and PTMC exhibit the same ultrasonographic features and behave same features is controversial. We aimed to evaluate the patients diagnosed with PTC and PTMC in terms of clinical, ultrasonographical (US) and histopathological features and their r...

Background: The characteristics of multifocal PTC remain controversial. Surgical approach to multifocal tumor changes between centers. In cases that the initial procedure was lobectomy, most clinicians would suggest for completion thyroidectomy since the risk of PTC in the contralateral lobe is significant. This study aimed to evaluate the incidence of bilateral involvement, predictive factors for bilaterality and whether or not bilaterality was related with more aggressive hi...

Aim: Cardiovascular morbidity and mortality of obesity is associated with classic risk factors, namely dyslipidaemia, hypertension and impaired glucose metabolism. Aim of this study is to evaluate inflammation as an independent risk factor by using neutrophil to lymphocyte ratio (NLR).Materials and methods: Patients who admitted to our outpatient clinic between January and December 2014 were assessed retrospectively. Patients diagnosed as diabetes, predi...

Several studies have reported that TSH is positively correlated with obesity, dyslipidaemia, and impaired glucose metabolism even in normal range limits. We aimed to evaluate the TSH levels in a cohort of otherwise healthy obese women without clinical evidence of thyroid dysfunction.Materials and methods: 127 female patients were enrolled in this study. Anthropometric and laboratory measurements were retrospectively analysed. Patients were divided into s...